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ansZ [2017-8-11 16:0:3]
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ansZ [2017-8-11 16:0:3]

asparaginase
locus
BSU02690
pI
6.15
mw
39.94 kDa
protein length
375 aa Sequence Blast
gene length
1125 bp Sequence Blast
function
asparagine utilization
product
asparaginase
essential
no
ec
3.5.1.1
synonyms
yccC
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.6|Utilization of asparagine/ aspartate]

    • Gene

    Coordinates
    290,915 → 292,042

    The protein

    Catalyzed reaction/ biological activity

  • L-asparagine H2O = L-aspartate NH3 (according to Swiss-Prot)

    • Protein family

  • asparaginase 2 family (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|FED8E46AA1C4EFD27796D5DFBBB1663EBF336BFD|AnsA]

    • Structure

  • [PDB|1ZCF] (from ''Pectobacterium atrosepticum scri1043'', 55% identity, 73% similarity)

    • Expression and Regulation

    Operons

    genes
    [gene|B5301B346FBAAE2D7C37D561FE1DCFDDFAC90D40|ansZ]
    description
    [Pubmed|11914346]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|11914346], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA]: activation, [Pubmed|11914346], in [regulon|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA regulon]
  • [protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY]: repression, [Pubmed|12618455], in [regulon|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY regulon]

    • regulation

  • expressed in the absence of good nitrogen sources (glutamine or ammonium) ([protein|search|TnrA]) [Pubmed|11914346]
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    References

  • 24003863,11914346,12618455,26672444,27796436